乳腺癌四肢长骨转移并发病理性骨折的手术治疗Surgical treatment for pathological fracture of long bone due to breast cancer metastasis
钱锦锋,叶招明
摘要(Abstract):
目的探讨乳腺癌四肢长骨转移并发病理性骨折的手术治疗。方法回顾性分析37例乳腺癌四肢长骨转移并发病理性骨折,采用手术治疗后临床症状改善状况。结果 37例中,所有患者术后疼痛明显缓解,术后患者的VAS评分为(4.35±1.72)分,低于术前的(7.39±1.53)分,差异有统计学意义(t=11.35,P<0.05)。37例患者肢体功能按Enneking评分[1]显示,优11例,良18例,中5例,差3例,优良率达78.4%。结论采用手术治疗乳腺癌四肢长骨转移并发骨折,可明显减轻患者的疼痛,提高其生活质量。
关键词(KeyWords): 乳腺肿瘤;肿瘤转移;骨肿瘤/外科学;骨肿瘤/继发性;四肢;骨折/外科学;疼痛;治疗结果;回顾性研究
基金项目(Foundation):
作者(Author): 钱锦锋,叶招明
DOI: 10.13267/j.cnki.syzlzz.2015.04.043
参考文献(References):
- [1]Akhtari M,Mensuri J,Newman KA,et al.Biology of breast cancer bone metastasis[J].Cancer Biol Ther,2008,7(1):3-9.
- [2]叶招明,杨迪生.转移性骨肿瘤的手术治疗[J].实用肿瘤杂志,2006,21(1):12-13.
- [3]Sarahrudik K,Greitbauer M,Platzer P,et al.Surgical treat-ment of metastatic fractures of the femur:a retrospective analysis of 142 patients[J].J Trauma,2009,66(4):1158-1163.
- [4]范顺武,杨迪生,陶惠民,等.手术治疗骨转移癌[J].中华骨科杂志,1999,19(1):24-27.
- [5]Kao CH,Hsieh JF,Tsai SC,et al.Comparison and discrepancy of18F-2-deoxyglucose positron emission tomography and Tc-99m MDP bone scan to detect bone metastases[J].Anticancer Res,2000,20(3B):2189-2192.
- [6]Gainor BJ,Buchert P.Fracture healing in metastatic bone disease[J].Clin Orthop,1983(178):297-302.
- [7]Lancaster JM,Koman LA,Gristina AG,et al.Pathologic fractures of the humerus[J].South Med J,1988,81(1):52-55.
- [8]邱梅清,佟仲生.老年乳腺癌临床特征预后多因素分析[J].实用肿瘤杂志,2013,28(2):162-166.