腹腔镜胰十二指肠切除术治疗胰头癌的技术策略和疗效评价
洪德飞
摘要(Abstract)：
<正>胰十二指肠切除术是唯一可能治愈胰头癌的治疗方式,但由于胰腺位于腹膜后,胰十二指肠切除术邻近血管多,切除脏器多,消化道重建复杂,至今仍是腹部外科最复杂和风险最高的手术,并发症发生率约50%,术后病死率1%～5%。术后胰瘘是引起患者再次手术和死亡的主要原因,术后胰瘘发生率10%～30%。虽然早在1994年Gagner等~([1])就首次报告腹腔镜胰十二指肠切除术(laparoscopic pancre-
关键词(KeyWords)： 胰腺肿瘤/外科学;胰十二指肠切除术/方法;手术期间;腹腔镜手术;剖腹术;治疗结果
基金项目(Foundation):
作者(Author): 洪德飞
DOI: 10.13267/j.cnki.syzlzz.2019.04.001
参考文献(References)：
- [1]Gagner M,Pomp A.Laparoscopic pylorus-preserving pancreatoduodenectomy[J].Surg Endosc,1994,8(5):408-410.
- [2]Pedrazzoli S,Di Carlo V,Dionigi R.et al.Standard versus extended lymphadenectomy associated with pancreatoduodenectomy in the surgical treatment of adenocarcinoma of the head of the pancreas:a multicenter,prospective,randomized study.Lymphadenectomy Study Group[J].Ann Surg,1998,228(4):508-517.
- [3]Yeo CJ,Cameron JL,Lillemoe KD.Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma,part 2:randomized controlled trial evaluating survival,morbidity,and mortality[J].Ann Surg,2002,236(3):355-366.
- [4]Nimura Y,Nagino M,Kato H,et al.Standard versus extended lymphadenectomy in radical pancreatoduodenectomy for ductal adencarcinoma of the head of the pancreas:long-term results of a Japanese muticenter randomized controlled trial[J].J Hepatobiliary Pancreat Sci,2012,19(3):230-241.
- [5]中华医学会外科学分会胰腺外科学组.胰腺癌诊治指南[J].中华外科杂志,2007,22(12):962-964.
- [6]洪德飞.学习曲线期安全开展腹腔镜胰十二指肠切除术的经验[J].中国实用外科杂志,2018,38(7):124-127.
- [7]洪德飞.开展腹腔镜胰十二指肠切除术的几个关键问题[J].中国实用外科杂志,2017,37(1):21-25.
- [8]洪德飞,刘亚辉,张宇华,等.腹腔镜胰十二指肠切除术中“洪氏一针法”胰管空肠吻合的临床应用[J].中华外科杂志,2017,55(2):136-140.
- [9]洪德飞,刘亚辉,张宇华,等.腹腔镜胰十二指肠切除术80例疗效分析[J].中国实用外科杂志,2016,36(8):885-888.
- [10]洪德飞,刘建华,刘亚辉,等.“一针法”胰肠吻合术用于腹腔镜胰十二指肠切除术多中心研究[J].中国实用外科杂志,2018,38(7):99-103.
- [11]中华医学会外科学分会胰腺外科学组等.腹腔镜胰十二指肠切除手术专家共识[J].中华外科杂志,2017,55(5):335-339.
- [12]Song CK,Song KB,Yong SJ,et al.Short-term clinical outcomes for 100 consecutive cases of laparoscopic pylorus-preserving pancreatoduodenectomy:improvement with surgical experience[J].Surg Endosc,2013,27(1):95.
- [13]Croome KP,Farnell MB,Que FG,et al.Total laparoscopic pancreaticoduodenectomy for pancreatic ductal adenocarcinoma:Oncologic advantages over open approaches?[J].Ann Surg,2014,260(4):633-640.
- [14]Edwin B,Sahakyan MA,Abu Hilal M,et al.Laparoscopic surgery for pancreatic neoplasms:the European association for endoscopic surgery clinical consensus conference[J].Surg Endosc,2017,31(5):2023-2041.
- [15]Senthilnathan P,Srivatsan S,Gul SI,et al.Long-term results of laparoscopic pancreaticoduodenectomy for pancreatic and periampullary cancer-experience of 130 cases from a tertiary-care center in South India[J].J Laparoendosc Adv Surg Tech,2015,25(4):295-300.
- [16]Stauffer JA,Coppola A,Villacreses D,et al.Laparoscopic versus open pancreaticoduodenectomy for pancreatic adenocarcinoma:long-term results at a single institution[J].Surg Endosc,2017,31(5):1-9.
- [17]van Hilst J,de Rooij T,Bosscha K,et al.Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours(LEOPARD-2):a multicentre,patient-blinded,randomised controlled phase 2/3 trial[J].Lancet Gastroenterol Hepatol,2019,4(3):199-207.
- [18]Croome KP,Farnell MB,Que FG,et al.Pancreaticoduodenectomy with major vascular resection:a comparison of laparoscopic versus open approaches[J].J Gastrointest Surg,2015,19(1):189-194.
- [19]洪德飞,张宇华,沈国樑,等.腹腔镜机器人联合血管切除重建的胰十二指肠切除术[J].中华肝胆外科杂志,2016,22(7):473-477.