非小细胞肺癌分子表型与EGFR-TKI治疗相关性研究进展
冯雪苹,宋鑫
摘要(Abstract):
<正>肺癌是目前世界上癌症死亡的主要原因[1],其中非小细胞肺癌(non-small cell lung cancer,NSCLC)占肺癌的80%~85%[2],大多数非小细胞肺癌患者确诊时已属ⅢB或Ⅳ期,尽管以铂类为基础的联合化疗使晚期NSCLC患者生存得到很大程
关键词(KeyWords): 癌,非小细胞肺;分子生物学;受体,表皮生长因子;酪氨酸激酶抑制剂;抗药性;治疗结果;药物疗法;预后
基金项目(Foundation): 国家高科技研究发展计划(863)(2012AA02A201);; 国家“十二·五”计划国家科技重大专项(2011ZX09102);; 国家自然科学基金(81060185,30671904,30760014);; 国家教育部新世纪优秀人才支持计划项目(NCET-08-0923);; 云南省科技计划项目-科技创新强省计划国际科技合作专项(2009AC016);; 云南省应用基础研究面上项目(2011FB209);; 云南省应用基础研究重点项目(2008CC006);; 云南省卫生科技计划项目(2010NS081,2009NS017);; 云南省卫生厅科技内设研究机构项目(2011WS0075);; 云南省教育厅科学研究基金项目(2011J043);; 昆明市科技计划重点项目(07S060202);; 昆明医学院研究生创新基金项目(2011N07);; 云南省引进高层次人才政府工作经费资助(60100122);; 高层次人才培引工程;; 云南省肿瘤医院肺癌防治省创新人才团队(20080C014);; 云南省一类省级肿瘤学重点学科建设项目基金;; 昆明医学院优先扶持肿瘤学重点学科建设项目基金
作者(Author): 冯雪苹,宋鑫
DOI: 10.13267/j.cnki.syzlzz.2012.05.029
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