闫圆圆,黄勇,李文武,白人驹,付政,穆殿斌,郭洪波

• 1:山东省肿瘤防治研究院影像中心/放射肿瘤学重点实验室

摘要(Abstract)：

目的探讨食管鳞癌FDG PET显像的最大标准摄取值(maximum FDG PET standardized uptake value,SUVmax)与肿瘤Ki-67表达及病理分级的关系。方法食管癌患者47例,于术前1周内行18F-FDG PET/CT检查,测得SUVmax。术后取得肿瘤标本,行Ki-67免疫组织化学染色,并HE染色确定病理分级,分析SUVmax、Ki-67、病理分级之间的关系。结果 (1)47例患者中共47个食管鳞癌原发病灶,SUVmax为1.9～24.0,平均为12.504±6.805,Ki-67平均指数为(67.837±29.798)%,经统计学分析,SUVmax与Ki-67指数呈正相关r,值为0.581,P<0.05。(2)47例中高分化鳞癌13例,中分化鳞癌16例,低分化鳞癌18例。高、中、分化鳞癌的平均SUVmax分别为9.787±1.4771、2.313±0.479和15.053±2.147,经统计学分析,三者之间差异均有统计学意义(P=0.000)。结论 SUVmax可间接评价食管癌细胞的增殖能力,SUVmax在一定程度上能够反映肿瘤的病理分级。

关键词(KeyWords)： 食管肿瘤;脱氧葡萄糖;断层摄影术,正电子发射型;体层摄影术,X线计算机;预后

Abstract:

Keywords:

基金项目(Foundation):

作者(Author): 闫圆圆,黄勇,李文武,白人驹,付政,穆殿斌,郭洪波

DOI: 10.13267/j.cnki.syzlzz.2011.05.020

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