DNA损伤修复基因Mus81在肿瘤发生中的作用
龙俊任,熊飞,董自强
摘要(Abstract):
通过对DNA损伤修复基因Mus81的特殊结构、生物学特性与肿瘤发生关系的探讨,反映Mus81在保持染色体的稳定性和抑制肿瘤中重要的生物学作用,为提高放疗、化疗疗效和克服肿瘤耐药提供新的理论依据和治疗思路。现就哺乳动物Mus81在肿瘤发生中的相关作用机制作一综述。
关键词(KeyWords): 肿瘤;DNA修复;Mus81基因;抗药性,肿瘤
基金项目(Foundation):
作者(Author): 龙俊任,熊飞,董自强
DOI: 10.13267/j.cnki.syzlzz.2011.05.030
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